n the course of investigations against Jack the Ripper, Francis J. Tumblety, a high-force, who disputes as a doctor, is arrested but then set free against bail. He flees to the United States, to New York, Manhattan. Accused by British colleagues, the New York police are looking for Tumblety. Witnesses want to have seen him in Manhattan and crimes are committed that carry all his handwriting. The police then asks the most famous personalities of the city for help. Mr. Jack in New York is a completely standalone game that can be played even if you do not know or own the previous editions.